The Cornell Center for Enervating Neuroimmune Disease conducts collaborative biomedical research to better understand ME/CFS, identify biological mechanisms and biomarkers, and support progress toward improved diagnosis, prevention, and treatment.

Our research brings together investigators across disciplines to examine immune, molecular, metabolic, genetic, and physiological changes associated with ME/CFS. Explore the Center’s current work, past research projects, and publications below.

Research at the Center

• Current and Ongoing Research — Learn about the Center’s active research projects, including studies of participant interactions, muscle tissue, immune cell dysfunction, extracellular vesicles, cell-free RNA, multiomics, and data integration.
• Past Research Projects — Explore completed and previous Center projects that have contributed to the scientific understanding of ME/CFS.
• Publications — Browse peer-reviewed articles, reports, and other publications from Center investigators and collaborators.

Current Research Areas

Current Center research includes investigations of how ME/CFS affects the immune system, cellular function, blood-based biomarkers, and physiological responses to exertion. The Center’s Research Core supports these efforts through bioinformatics, data management, and data integration.

• Participant Interactions
• Differential Gene Expression in Muscle Cells
• Immune Dysregulation in Classical Monocytes and Platelets
• Extracellular Vesicle Cargo
• Cell-free RNA in Plasma
• Multiomics Correlations Between Different Data Types
• Research Core

View all current and ongoing research projects