Dr. Arnaud Germain, a member of the Hanson Lab, is the lead author on a new publication in the journal Metabolites. The paper describes a metabolomics study on the plasma of 52 female subjects. A large emphasis on lipids was observed in the approximately 1,750 blood compound datapoints. As summarized in the illustration below, notable changes were uncovered when comparing the ME/CFS and control cohorts.
The Trans-NIH ME/CFS Working Group announced an upcoming public lecture at the Masur Auditorium in NIH’s Clinical Center. Cornell ENID Center members Dr. Maureen Hanson and Dr. Betsy Keller will be presenting, and the event will also include updates on the NIH intramural study. The event will be hosted by the NIH ME/CFS Special Interest Group and is scheduled to take place on April 22, 2020 at 12:30 pm. Anyone that is interested can attend in person or watch the talks via videocast.
This post will be updated with the videocast link and other pertinent event information as it is made available. Also, you can receive updates and other NIH ME/CFS information by joining the NIH ME/CFS listserv. Visit the subscription link here if you are interested in subscribing.
Event information: https://www.nih.gov/mecfs/events
UPDATE: The Trans-NIH ME/CFS WG announced on 3/23/2020 that this event will be postponed due to the coronavirus situation.
The ENID Center is excited to announce a new publication in the Journal of Clinical Investigation. Recent Hanson Lab graduate, Dr. Alexandra Mandarano, is the lead author of “Myalgic encephalomyelitis/chronic fatigue syndrome patients exhibit altered T cell metabolism and cytokine associations”. This paper goes into our research exploring the immune system in people with ME/CFS.
UPDATE: The final publication of the paper was released on February 10, 2020. Accompanying this release, Dr. Mady Hornig wrote a related commentary: “Can the light of immunometabolism cut through “brain fog”?“.
Dr. Daniel Peterson and Simmaron Research staff Dr. Gunnar Gottschalk and Marco Maynard provided blood samples from carefully diagnosed ME/CFS cases and controls that were critical for carrying out the study. Thanks to Simmaron Research and a private donor, as well as NIH, for financial support for the study. A press release was issued by NIH.
Furthermore, we have launched a new initiative to help expand the reach of our research. Dr. Mandarano has recorded a talk that walks you through this publication. The video is hosted on our new YouTube channel. Check out this video below and stay tuned for future posts and videos about our research.
As part of the Norwegian ME Association’s Knowledge Campaign 2019, Dr. Betsy Keller traveled to Norway to present on post-exertional malaise. The Norwegian ME Association has uploaded her talk to YouTube and can be watched using the embedded video below. Additionally, the following links will direct you to associated information translated to English via Google Translate.
A Norwegian blog, The Hidden, published a summary of our NIH funded research center efforts. The blog is by physical therapist and journalist Jørgen Jelstad. He covers various aspects relating to ME/CFS and has also reviewed the other two NIH funded research centers—Columbia’s Center for Solutions for ME/CFS and The Jackson Laboratory’s Collaborative Research Center. For an English translation of the website by Google Translate iTool, please visit this link.
In November 2019, the Cornell Office of the Vice Provost for Research featured on their website the ME/CFS projects as well as some plant projects ongoing in Dr. Maureen Hanson‘s lab at Cornell See a set of photos and an article here: “A Researcher’s Duality: Plants, Biomedical”.
Members of the Cornell ME/CFS Center joined advocacy representatives, Columbia Center for Solutions, JAX ME/CFS Center, NIH, and RTI for the second annual ME/CFS Consortium meeting. The group met in New York City on October 22 and 23, 2019 to discuss current research progress and future collaborative efforts.
A generous donor has offered to match up to $25,000 in donations to the Cornell Center for Enervating Neuroimmune Disease for our work on immune dysregulation in ME/CFS, which was recently described in Dr. Maureen Hanson’s talk at the Stanford OMF Community Symposium.
Please visit our donation page if you wish to support our work on the immune system in ME/CFS. All donations are gratefully received.
The Third Annual Community Symposium on the Molecular Basis of ME/CFS followed the Open Medicine Foundation working group meeting at Stanford University on September 7th, 2019. Keynote speaker, Dr. Maureen Hanson, started her talk discussing data on metabolomics, immune cells, extracellular vesicles, and RNA gene expression. The second portion of her talk went into her thoughts on the disease. OMF has uploaded her talk to YouTube, which can be found here.
The Open Medicine Foundation held their third annual collaborative team meeting on ME/CFS. Dr. Maureen Hanson joined approximately 60 other researchers at Standford University from September 4th to 6th, 2019 to discuss their latest unpublished and preliminary data on the disease. A diverse field of scientific topics were discussed as noted in the agenda.