Center Director Dr. Maureen Hanson will be presenting current scientific research on ME/CFS during a panel session hosted by New York State Department of Health (NYS DOH). The session titled “Scientific Research on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome in the Age of COVID-19” will be moderated by Dr. Charles Gonzalez. Dr. Ian Lipkin (Columbia University) and Dr. Avindra Nath (NIH) will be joining Hanson as panel presenters.
UPDATE: In case you missed the panel discussion, NYS DOH released a recording along with each presenter’s slides. Direct links to the recording and Dr. Hanson’s slides are below. Visit the NYS DOH ME/CFS website for more information.
Hanson Lab alumna, Alexandra Mandarano ’19 Ph.D., received the Laboratory Product Sales (LPS) award for her December 2019 JCI publication. The LPS award is granted to a student of the graduate field Genomics, Genomics and Development who is first author on what is judged to be the “best” student paper published in a calendar year. The award includes Mandarano’s name engraved on a plaque in the Department of Molecular Biology and Genetics office. Congratulations, Dr. Mandarano!
This methodologically focused review covers aspects of ME/CFS pathophysiology that are consistent with chronic enterovirus infection outcomes and then closely examines the technology used in in past ME/CFS publications to determine how rigorously the enterovirus theory of disease etiology has been investigated.
IACFSME held a virtual medical and scientific research conference on July 27-30, 2022. Our Center presented several talks and participated in the poster session at the conference. Center members Andrew Grimson, Arnaud Germain, Betsy Keller, Geoff Moore, Jessica Maya, and Katie Glass gave oral presentation on topics ranging from immune cell exhaustion to post CPET recovery. Postdoctoral associate, Ludovic Giloteaux, presented a poster on extracellular vesicle proteins in plasma. Details about the conference agenda can be found on the event’s website.
We would also like to announce that Candace Receno, a new collaborator at Ithaca College, and Jessica Maya received the NIH NINDS travel award at this year’s meeting. Congratulations to Candace and Jessica!
This study, led by Adam O’Neal, analyzed plasma antibodies to 122 different pathogen antigens in a case-control comparison including 103 individuals. The cohort of 59 ME/CFS and 44 healthy controls included both female and male participants. The anti-pathogen antibody assays were performed by Augmenta Bioworks. Although this study did not find one particular pathogen associated with ME/CFS, sex-based differences were uncovered. Check out this publication (link above) for more information.
For International ME/CFS Awareness Day, we would like to announce the official publication of a large metabolomics study from our Center. The work led by Arnaud Germain, PhD, describes results from a longitudinal plasma metabolite study associated with a 2-day cardiopulmonary exercise test (CPET). Over 100 individuals, including both females and males, were assayed before and after both days of the 2-day CPET. The article is open access in the journal JCI Insight. The quote below, from this publication, does an excellent job at summarizing the study.
Our longitudinal study design has allowed us to identify a number of pathways that diverge between healthy individuals and those with ME/CFS 24 hours after an exercise challenge, at which time patients typically experience PEM. Inability to recover properly after exertion is one of the most disabling symptoms of ME/CFS. Our study provides insight into the metabolic changes that are inimical to proper response to physical effort.
The Trans-NIH ME/CFS Working Group announced an upcoming public lecture at the Masur Auditorium in NIH’s Clinical Center. Cornell ENID Center members Dr. Maureen Hanson and Dr. Betsy Keller will be presenting, and the event will also include updates on the NIH intramural study. The event will be hosted by the NIH ME/CFS Special Interest Group and is scheduled to take place on April 22, 2020 at 12:30 pm. Anyone that is interested can attend in person or watch the talks via videocast.
This post will be updated with the videocast link and other pertinent event information as it is made available. Also, you can receive updates and other NIH ME/CFS information by joining the NIH ME/CFS listserv. Visit the subscription link here if you are interested in subscribing.
Members of the Cornell ME/CFS Center joined advocacy representatives, Columbia Center for Solutions, JAX ME/CFS Center, NIH, and RTI for the second annual ME/CFS Consortium meeting. The group met in New York City on October 22 and 23, 2019 to discuss current research progress and future collaborative efforts.
A generous donor has offered to match up to $25,000 in donations to the Cornell Center for Enervating Neuroimmune Disease for our work on immune dysregulation in ME/CFS, which was recently described in Dr. Maureen Hanson’s talk at the Stanford OMF Community Symposium.
Please visit our donation page if you wish to support our work on the immune system in ME/CFS. All donations are gratefully received.
The Open Medicine Foundation held their third annual collaborative team meeting on ME/CFS. Dr. Maureen Hanson joined approximately 60 other researchers at Standford University from September 4th to 6th, 2019 to discuss their latest unpublished and preliminary data on the disease. A diverse field of scientific topics were discussed as noted in the agenda.