Altered T cell metabolism and dysregulated cytokine associations in ME/CFS

The ENID Center is excited to announce a new publication in the Journal of Clinical Investigation. Recent Hanson Lab graduate, Dr. Alexandra Mandarano, is the lead author of “Myalgic encephalomyelitis/chronic fatigue syndrome patients exhibit altered T cell metabolism and cytokine associations”. This paper goes into our research exploring the immune system in people with ME/CFS.

UPDATE: The final publication of the paper was released on February 10, 2020. Accompanying this release, Dr. Mady Hornig wrote a related commentary: “Can the light of immunometabolism cut through “brain fog”?“.

Dr. Daniel Peterson and Simmaron Research staff Dr. Gunnar Gottschalk and Marco Maynard provided blood samples from carefully diagnosed ME/CFS cases and controls that were critical for carrying out the study.  Thanks to Simmaron Research and a private donor, as well as NIH, for financial support for the study.  A press release was issued by NIH.

Furthermore, we have launched a new initiative to help expand the reach of our research. Dr. Mandarano has recorded a talk that walks you through this publication. The video is hosted on our new YouTube channel. Check out this video below and stay tuned for future posts and videos about our research.

Betsy Keller speaks in Norway November 2019

As part of the Norwegian ME Association’s Knowledge Campaign 2019, Dr. Betsy Keller traveled to Norway to present on post-exertional malaise. The Norwegian ME Association has uploaded her talk to YouTube and can be watched using the embedded video below. Additionally, the following links will direct you to associated information translated to English via Google Translate.

Norwegian ME Association’s Knowledge Campaign 2019

Post about Dr. Keller’s talk including information on PEM management

 

ENID Center featured in Norwegian blog

Quote translation: “… how ME became the most contentious disease of our time”
Photo: De Bortgjemte (The Hidden)

A Norwegian blog, The Hidden, published a summary of our NIH funded research center efforts.  The blog is by physical therapist and journalist Jørgen Jelstad. He covers various aspects relating to ME/CFS and has also reviewed the other two NIH funded research centers—Columbia’s Center for Solutions for ME/CFS and The Jackson Laboratory’s Collaborative Research Center. For an English translation of the website by Google Translate iTool, please visit this link.